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Target
Indolethylamine N-methyltransferase
Ligand
BDBM50000094
Substrate
n/a
Meas. Tech.
ChEMBL_1333668 (CHEMBL3231054)
IC50
800±n/a nM
Citation
 Rokach, J; Hamel, P; Hunter, NR; Reader, G; Rooney, CS; Anderson, PS; Cragoe, EJ; Mandel, LR Cyclic amidine inhibitors of indolamine N-methyltransferase. J Med Chem 22:237-47 (1979) [PubMed]  Article 
Target
Name:
Indolethylamine N-methyltransferase
Synonyms:
Amine N-methyltransferase | Aromatic alkylamine N-methyltransferase | Arylamine N-methyltransferase | INMT | INMT_HUMAN | Indolamine N-methyltransferase
Type:
PROTEIN
Mol. Mass.:
28884.19
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1333668
Residue:
263
Sequence:
MKGGFTGGDEYQKHFLPRDYLATYYSFDGSPSPEAEMLKFNLECLHKTFGPGGLQGDTLIDIGSGPTIYQVLAACDSFQDITLSDFTDRNREELEKWLKKEPGAYDWTPAVKFACELEGNSGRWEEKEEKLRAAVKRVLKCDVHLGNPLAPAVLPLADCVLTLLAMECACCSLDAYRAALCNLASLLKPGGHLVTTVTLRLPSYMVGKREFSCVALEKEEVEQAVLDAGFDIEQLLHSPQSYSVTNAANNGVCFIVARKKPGP
  
Inhibitor
Name:
BDBM50000094
Synonyms:
CHEMBL3228343
Type:
Small organic molecule
Emp. Form.:
C11H16N2O4
Mol. Mass.:
240.2557
SMILES:
OC(=O)\C=C\C(O)=O.C1CN2CCCCC2=N1 |c:15|
Structure:
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