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Target
Thymidine kinase, cytosolic
Ligand
BDBM50000979
Substrate
n/a
Meas. Tech.
ChEMBL_1333876 (CHEMBL3231765)
Ki
500000±n/a nM
Citation
 Hampton, A; Kappler, F; Chawla, RR Design of species- or isozyme-specific enzyme inhibitors. 1. Effect of thymidine substituents on affinity for the thymidine site of hamster cytoplasmic thymidine kinase. J Med Chem 22:621-31 (1979) [PubMed]  Article 
Target
Name:
Thymidine kinase, cytosolic
Synonyms:
KITH_CRIGR | TK1
Type:
PROTEIN
Mol. Mass.:
25628.94
Organism:
Cricetulus griseus
Description:
ChEMBL_108265
Residue:
234
Sequence:
MNYINLPTVLPGSPSKTRGQIQVILGPMFSGKSTELMRRVRRFQIAQNKCLVIKYAKDTRYSSSFSTHDRNTMDALPACLLRDVAQEALGAAVIGIDEGQFFPDIVEFCEVMANAGKTVIVAALDGTFQRKAFGSILNLVPLAESVVKLTAVCMECFREAAYTKRLGLEKEVEVIGGADKYHSVCRVCYFKKSSVQPAGPDNKENCPVLGQPGEASAVRKLFAPQQVLQHNSTN
  
Inhibitor
Name:
BDBM50000979
Synonyms:
CHEMBL3229807
Type:
Small organic molecule
Emp. Form.:
C13H18N2O6S
Mol. Mass.:
330.357
SMILES:
Cc1cn([C@H]2C[C@H](O)[C@@H](CSCCC(O)=O)O2)c(=O)[nH]c1=O |r|
Structure:
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