Reaction Details Report a problem with these data
Target
Carbonic anhydrase 2
Ligand
BDBM50004260
Substrate
n/a
Meas. Tech.
ChEMBL_1335178 (CHEMBL3239762)
IC50
1280±n/a nM
Citation
 Zaib, S; Saeed, A; Stolte, K; Flörke, U; Shahid, M; Iqbal, J New aminobenzenesulfonamide-thiourea conjugates: synthesis and carbonic anhydrase inhibition and docking studies. Eur J Med Chem 78:140-50 (2014) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 2
Synonyms:
CA2 | CAH2_BOVIN | Carbonic anhydrase | Carbonic anhydrase 2 | Carbonic anhydrase II | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29115.93
Organism:
Bos taurus
Description:
n/a
Residue:
260
Sequence:
MSHHWGYGKHNGPEHWHKDFPIANGERQSPVDIDTKAVVQDPALKPLALVYGEATSRRMVNNGHSFNVEYDDSQDKAVLKDGPLTGTYRLVQFHFHWGSSDDQGSEHTVDRKKYAAELHLVHWNTKYGDFGTAAQQPDGLAVVGVFLKVGDANPALQKVLDALDSIKTKGKSTDFPNFDPGSLLPNVLDYWTYPGSLTTPPLLESVTWIVLKEPISVSSQQMLKFRTLNFNAEGEPELLMLANWRPAQPLKNRQVRGFPK
  
Inhibitor
Name:
BDBM50004260
Synonyms:
CHEMBL3237499
Type:
Small organic molecule
Emp. Form.:
C12H17N3O3S2
Mol. Mass.:
315.412
SMILES:
CC(C)(C)C(=O)NC(=S)Nc1cccc(c1)S(N)(=O)=O
Structure:
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