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Target
Proteasome subunit beta type-1
Ligand
BDBM50007719
Substrate
n/a
Meas. Tech.
ChEMBL_1334924 (CHEMBL3239240)
Ki
22300±n/a nM
Citation
 Scarbaci, K; Troiano, V; Micale, N; Ettari, R; Tamborini, L; Di Giovanni, C; Cerchia, C; Grasso, S; Novellino, E; Schirmeister, T; Lavecchia, A; Zappalą, M Identification of a new series of amides as non-covalent proteasome inhibitors. Eur J Med Chem 76:1-9 (2014) [PubMed]  Article 
Target
Name:
Proteasome subunit beta type-1
Synonyms:
PSB1_HUMAN | PSC5 | PSMB1 | Proteasome component C5 | Proteasome subunit beta type-1/beta type-5
Type:
PROTEIN
Mol. Mass.:
26493.62
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1366691
Residue:
241
Sequence:
MLSSTAMYSAPGRDLGMEPHRAAGPLQLRFSPYVFNGGTILAIAGEDFAIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLTKIIEARLKMYKHSNNKAMTTGAIAAMLSTILYSRRFFPYYVYNIIGGLDEEGKGAVYSFDPVGSYQRDSFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLSLDRAMRLVKDVFISAAERDVYTGDALRICIVTKEGIREETVSLRKD
  
Inhibitor
Name:
BDBM50007719
Synonyms:
CHEMBL3233441
Type:
Small organic molecule
Emp. Form.:
C15H18BrN3O2
Mol. Mass.:
352.226
SMILES:
CC(C)CCNC(=O)Cn1cc(Br)c2ncccc2c1=O
Structure:
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