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Target
Chromobox protein homolog 1
Ligand
BDBM50009555
Substrate
n/a
Meas. Tech.
ChEMBL_1336415 (CHEMBL3242419)
Kd
>500000±n/a nM
Citation
 Simhadri, C; Daze, KD; Douglas, SF; Quon, TT; Dev, A; Gignac, MC; Peng, F; Heller, M; Boulanger, MJ; Wulff, JE; Hof, F Chromodomain antagonists that target the polycomb-group methyllysine reader protein chromobox homolog 7 (CBX7). J Med Chem 57:2874-83 (2014) [PubMed]  Article 
Target
Name:
Chromobox protein homolog 1
Synonyms:
CBX | CBX1 | CBX1_HUMAN | HP1 beta | HP1Hsbeta | Heterochromatin protein 1 homolog beta | Heterochromatin protein p25 | M31 | Modifier 1 protein | p25beta
Type:
PROTEIN
Mol. Mass.:
21405.43
Organism:
Homo sapiens (Human)
Description:
ChEMBL_103989
Residue:
185
Sequence:
MGKKQNKKKVEEVLEEEEEEYVVEKVLDRRVVKGKVEYLLKWKGFSDEDNTWEPEENLDCPDLIAEFLQSQKTAHETDKSEGGKRKADSDSEDKGEESKPKKKKEESEKPRGFARGLEPERIIGATDSSGELMFLMKWKNSDEADLVPAKEANVKCPQVVISFYEERLTWHSYPSEDDDKKDDKN
  
Inhibitor
Name:
BDBM50009555
Synonyms:
CHEMBL3234443
Type:
Small organic molecule
Emp. Form.:
C40H59N6O9
Mol. Mass.:
767.9307
SMILES:
COC(=O)c1ccc(cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](C1CCCC1)C(=O)N[C@@H](CCCC[N+](C)(C)C)C(=O)NC(CO)CO |r|
Structure:
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