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Target
G-protein coupled receptor 183
Ligand
BDBM50011689
Substrate
n/a
Meas. Tech.
ChEMBL_1351309 (CHEMBL3266158)
IC50
21±n/a nM
Citation
 Gessier, F; Preuss, I; Yin, H; Rosenkilde, MM; Laurent, S; Endres, R; Chen, YA; Marsilje, TH; Seuwen, K; Nguyen, DG; Sailer, AW Identification and characterization of small molecule modulators of the Epstein-Barr virus-induced gene 2 (EBI2) receptor. J Med Chem 57:3358-68 (2014) [PubMed]  Article 
Target
Name:
G-protein coupled receptor 183
Synonyms:
EBV-induced G-protein coupled receptor 2 | Ebi2 | Epstein-Barr virus-induced G-protein coupled receptor 2 | GP183_MOUSE | Gpr183
Type:
PROTEIN
Mol. Mass.:
40205.57
Organism:
Mus musculus
Description:
ChEMBL_108312
Residue:
357
Sequence:
MANNFTTPLATSHGNNCDLYAHHSTARVLMPLHYSLVFIIGLVGNLLALVVIVQNRKKINSTTLYSMNLVISDILFTTALPTRIAYYALGFDWRIGDALCRVTALVFYINTYAGVNFMTCLSIDRFFAVVHPLRYNKIKRIEYAKGVCLSVWILVFAQTLPLLLTPMSKEEGDKTTCMEYPNFEGTASLPWILLGACLLGYVLPITVILLCYSQICCKLFRTAKQNPLTEKSGVNKKALNTIILIIVVFILCFTPYHVAIIQHMIKMLCSPGALECGARHSFQISLHFTVCLMNFNCCMDPFIYFFACKGYKRKVMKMLKRQVSVSISSAVRSAPEENSREMTESQMMIHSKASNGR
  
Inhibitor
Name:
BDBM50011689
Synonyms:
CHEMBL3262892
Type:
Small organic molecule
Emp. Form.:
C22H23ClN2O3
Mol. Mass.:
398.883
SMILES:
COc1ccc(\C=C\C(=O)N2CCN(CC2)C(=O)c2ccc(Cl)c(C)c2)cc1
Structure:
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