Reaction Details Report a problem with these data
Target
Cytohesin-3
Ligand
BDBM50013327
Substrate
n/a
Meas. Tech.
ChEMBL_1348972 (CHEMBL3265619)
IC50
38000±n/a nM
Citation
 Kim, Y; Yoon, Y Elucidation of different inhibition mechanism of small chemicals on PtdInsP-binding domains using in silico docking experiments. Bioorg Med Chem Lett 24:2256-62 (2014) [PubMed]  Article 
Target
Name:
Cytohesin-3
Synonyms:
ARNO3 | CYH3_HUMAN | CYTH3 | GRP1 | General receptor of phosphoinositides 1 (GRP1) | PSCD3
Type:
Enzyme
Mol. Mass.:
46340.05
Organism:
Homo sapiens (Human)
Description:
O43739
Residue:
400
Sequence:
MDEDGGGEGGGVPEDLSLEEREELLDIRRRKKELIDDIERLKYEIAEVMTEIDNLTSVEESKTTQRNKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGDYLGERDEFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCNPGVFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTAERFIAMNRGINEGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASISRDPFYDMLATRKRRIANKK
  
Inhibitor
Name:
BDBM50013327
Synonyms:
CHEMBL3263343
Type:
Small organic molecule
Emp. Form.:
C4H5N2O5P
Mol. Mass.:
192.0667
SMILES:
OC(=O)c1cc(n[nH]1)P(O)(O)=O
Structure:
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