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Target
D-alanyl-D-alanine dipeptidase
Ligand
BDBM50014161
Substrate
n/a
Meas. Tech.
ChEMBL_1350288 (CHEMBL3267626)
Ki
2740±n/a nM
Citation
 Muthyala, R; Rastogi, N; Shin, WS; Peterson, ML; Sham, YY Cell permeable vanX inhibitors as vancomycin re-sensitizing agents. Bioorg Med Chem Lett 24:2535-8 (2014) [PubMed]  Article 
Target
Name:
D-alanyl-D-alanine dipeptidase
Synonyms:
D-Ala-D-Ala dipeptidase | VANX_ENTFC | Vancomycin B-type resistance protein vanX | vanX
Type:
PROTEIN
Mol. Mass.:
23377.40
Organism:
Enterococcus faecium
Description:
ChEMBL_1350288
Residue:
202
Sequence:
MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTYELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRTEMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEAQNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK
  
Inhibitor
Name:
BDBM50014161
Synonyms:
CHEMBL3260858 | US11491146, Compound 5
Type:
Small organic molecule
Emp. Form.:
C14H12N2O4S
Mol. Mass.:
304.321
SMILES:
OC(=O)[C@H](NC(=O)c1cccc(=S)n1O)c1ccccc1 |r|
Structure:
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