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Target
Histamine N-methyltransferase
Ligand
BDBM50016547
Substrate
n/a
Meas. Tech.
ChEMBL_1357416 (CHEMBL3281574)
Ki
247000±n/a nM
Citation
 Ahmed, AE; Hanna, PE; Grund, VR Conformationally restricted analogs of histamine H1 receptor antagonists: trans and cis-1-benzyl-3-dimethylamino-6-phenylpiperidine. J Med Chem 19:117-22 (1976) [PubMed]  Article 
Target
Name:
Histamine N-methyltransferase
Synonyms:
HMT | HNMT | HNMT_CAVPO
Type:
PROTEIN
Mol. Mass.:
33709.50
Organism:
Cavia porcellus
Description:
ChEMBL_100022
Residue:
292
Sequence:
MASSMRSLFSDHGRYFEAFRRFLNNSTEYQCMREFMDKQLPGIIARIGGSKSEIKVLSIGGGAGEMDLHILSKVKAQYPGVHIINEVVEPSAEQITKYKELVAKTSNLENIKFAWHKETSSEYQNRVMEQKEIQKWDFIHMIQMLYYVDDIPATLKFFHSLLATNAKILIILVSGKSGWLKFWKKYRSRLPQNDLCQYVTSFDIIQMLDSLGIKYQCYDLLSTMDITDCFIDGNENGELLWDFLTETCNFLTTAPPDLRAEIMKDLQGPEFIVRKEGKILFDNSLSFITIEA
  
Inhibitor
Name:
BDBM50016547
Synonyms:
CHEMBL3272447
Type:
Small organic molecule
Emp. Form.:
C20H26N2
Mol. Mass.:
294.4338
SMILES:
CN(C)[C@H]1CC[C@@H](N(Cc2ccccc2)C1)c1ccccc1 |r|
Structure:
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