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Target
Amine oxidase [flavin-containing] A
Ligand
BDBM50159254
Substrate
n/a
Meas. Tech.
ChEMBL_1363618 (CHEMBL3292881)
IC50
14800±n/a nM
Citation
 Legoabe, LJ; Petzer, A; Petzer, JP a-Tetralone derivatives as inhibitors of monoamine oxidase. Bioorg Med Chem Lett 24:2758-63 (2014) [PubMed]  Article 
Target
Name:
Amine oxidase [flavin-containing] A
Synonyms:
AOFA_HUMAN | Amine oxidase (flavin-containing) A | MAO-A | MAOA | Monoamine oxidase | Monoamine oxidase type A | Monoamine oxidase type A (MAO A) | Monoamine oxidase type A (MAO A) | Monoamine oxidase type A (MAOA)
Type:
Protein
Mol. Mass.:
59689.53
Organism:
Homo sapiens (Human)
Description:
P21397
Residue:
527
Sequence:
MENQEKASIAGHMFDVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTIRNEHVDYVDVGGAYVGPTQNRILRLSKELGIETYKVNVSERLVQYVKGKTYPFRGAFPPVWNPIAYLDYNNLWRTIDNMGKEIPTDAPWEAQHADKWDKMTMKELIDKICWTKTARRFAYLFVNINVTSEPHEVSALWFLWYVKQCGGTTRIFSVTNGGQERKFVGGSGQVSERIMDLLGDQVKLNHPVTHVDQSSDNIIIETLNHEHYECKYVINAIPPTLTAKIHFRPELPAERNQLIQRLPMGAVIKCMMYYKEAFWKKKDYCGCMIIEDEDAPISITLDDTKPDGSLPAIMGFILARKADRLAKLHKEIRKKKICELYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYGRVIRQPVGRIFFAGTETATKWSGYMEGAVEAGERAAREVLNGLGKVTEKDIWVQEPESKDVPAVEITHTFWERNLPSVSGLLKIIGFSTSVTALGFVLYKYKLLPRS
  
Inhibitor
Name:
BDBM50159254
Synonyms:
3,4-Dihydro-2H-naphthalen-1-one | 3,4-dihydronaphthalen-1(2H)-one | CHEMBL193373
Type:
Small organic molecule
Emp. Form.:
C10H10O
Mol. Mass.:
146.1858
SMILES:
O=C1CCCc2ccccc12
Structure:
Search PDB for entries with ligand similarity: