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Target
G-protein coupled receptor 52
Ligand
BDBM50022254
Substrate
n/a
Meas. Tech.
ChEMBL_1367592
EC50
83±n/a nM
Citation
 Setoh, M; Ishii, N; Kono, M; Miyanohana, Y; Shiraishi, E; Harasawa, T; Ota, H; Odani, T; Kanzaki, N; Aoyama, K; Hamada, T; Kori, M Discovery of the first potent and orally available agonist of the orphan G-protein-coupled receptor 52. J Med Chem 57:5226-37 (2014) [PubMed]  Article 
Target
Name:
G-protein coupled receptor 52
Synonyms:
GPR52 | GPR52_HUMAN | Probable G-protein coupled receptor 52
Type:
PROTEIN
Mol. Mass.:
41366.15
Organism:
Homo sapiens (Human)
Description:
ChEMBL_108391
Residue:
361
Sequence:
MNESRWTEWRILNMSSGIVNVSERHSCPLGFGHYSVVDVCIFETVVIVLLTFLIIAGNLTVIFVFHCAPLLHHYTTSYFIQTMAYADLFVGVSCLVPTLSLLHYSTGVHESLTCQVFGYIISVLKSVSMACLACISVDRYLAITKPLSYNQLVTPCRLRICIILIWIYSCLIFLPSFFGWGKPGYHGDIFEWCATSWLTSAYFTGFIVCLLYAPAAFVVCFTYFHIFKICRQHTKEINDRRARFPSHEVDSSRETGHSPDRRYAMVLFRITSVFYMLWLPYIIYFLLESSRVLDNPTLSFLTTWLAISNSFCNCVIYSLSNSVFRLGLRRLSETMCTSCMCVKDQEAQEPKPRKRANSCSI
  
Inhibitor
Name:
BDBM50022254
Synonyms:
CHEMBL3298234
Type:
Small organic molecule
Emp. Form.:
C25H18F4N2O2S
Mol. Mass.:
486.481
SMILES:
NC(=O)CNC(=O)c1cccc(c1)-c1ccc(F)c2cc(Cc3cccc(c3)C(F)(F)F)sc12
Structure:
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