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Target
Env polyprotein
Ligand
BDBM23208
Substrate
n/a
Meas. Tech.
ChEMBL_1455137 (CHEMBL3366750)
EC50
>100000±n/a nM
Citation
 Wang, C; Lu, L; Na, H; Li, X; Wang, Q; Jiang, X; Xu, X; Yu, F; Zhang, T; Li, J; Zhang, Z; Zheng, B; Liang, G; Cai, L; Jiang, S; Liu, K Conjugation of a nonspecific antiviral sapogenin with a specific HIV fusion inhibitor: a promising strategy for discovering new antiviral therapeutics. J Med Chem 57:7342-54 (2014) [PubMed]  Article 
Target
Name:
Env polyprotein
Synonyms:
ENV | GP41 | HIV1
Type:
PROTEIN
Mol. Mass.:
14017.92
Organism:
Human immunodeficiency virus 1
Description:
ChEMBL_109731
Residue:
124
Sequence:
FLGFLGAAGSTMGAASITLTVQARTLLSGIVQQQNNLLRAIEAQQHLLQLTVWGIKQLQARVLAVERYLQDQQLLGIWGCSGKHICTTTVPWNSSWSNKSLEEIWQNMTWMEWEREIDNYTGLI
  
Inhibitor
Name:
BDBM23208
Synonyms:
(1R,2R,5S,8R,9R,10R,13R,14R,17S,19R)-17-hydroxy-1,2,14,18,18-pentamethyl-8-(prop-1-en-2-yl)pentacyclo[11.8.0.0^{2,10}.0^{5,9}.0^{14,19}]henicosane-5-carboxylic acid | Betulinic Acid, 24 | CHEMBL269277 | cid_64971
Type:
Terpene
Emp. Form.:
C30H48O3
Mol. Mass.:
456.7003
SMILES:
[H][C@]12[C@@H](CC[C@@]1(CC[C@]1(C)[C@]2([H])CC[C@]2([H])[C@@]3(C)CC[C@H](O)C(C)(C)[C@]3([H])CC[C@@]12C)C(O)=O)C(C)=C
Structure:
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