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Target
Mu-type opioid receptor
Ligand
BDBM50028060
Substrate
n/a
Meas. Tech.
ChEMBL_1434014 (CHEMBL3381486)
Ki
>1000±n/a nM
Citation
 Hirayama, S; Wada, N; Kuroda, N; Iwai, T; Yamaotsu, N; Hirono, S; Fujii, H; Nagase, H Synthesis of a novel universal opioid receptor agonist with the 1,3,5-trioxazatriquinane skeleton and its pharmacologies. Bioorg Med Chem Lett 24:4895-8 (2014) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mor | OPIATE Mu | OPRM_MOUSE | Opioid receptors; mu and delta | Oprm | Oprm1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44431.62
Organism:
MOUSE
Description:
OPIATE Mu OPRM1 MOUSE::P42866
Residue:
398
Sequence:
MDSSAGPGNISDCSDPLAPASCSPAPGSWLNLSHVDGNQSDPCGPNRTGLGGSHSLCPQTGSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGNILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQQNSARIRQNTREHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50028060
Synonyms:
CHEMBL3338872
Type:
Small organic molecule
Emp. Form.:
C27H27NO6
Mol. Mass.:
461.5064
SMILES:
[H][C@]12O[C@](C)(c3ccc(O)cc3)[C@]3([H])O[C@@](C)(c4ccc(O)cc4)[C@]([H])(O[C@]1(C)c1ccc(O)cc1)N23 |r|
Structure:
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