Reaction Details Report a problem with these data
Target
Neuropeptide FF receptor 1
Ligand
BDBM50029097
Substrate
n/a
Meas. Tech.
ChEMBL_1436238 (CHEMBL3387185)
Ki
112±n/a nM
Citation
 Journigan, VB; Mésangeau, C; Vyas, N; Eans, SO; Cutler, SJ; McLaughlin, JP; Mollereau, C; McCurdy, CR Nonpeptide small molecule agonist and antagonist original leads for neuropeptide FF1 and FF2 receptors. J Med Chem 57:8903-27 (2014) [PubMed]  Article 
Target
Name:
Neuropeptide FF receptor 1
Synonyms:
G-protein coupled receptor 147 | GPR147 | NPFF1 | NPFF1_HUMAN | NPFFR1 | RFamide-related peptide receptor OT7T022
Type:
PROTEIN
Mol. Mass.:
47840.07
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1474637
Residue:
430
Sequence:
MEGEPSQPPNSSWPLSQNGTNTEATPATNLTFSSYYQHTSPVAAMFIVAYALIFLLCMVGNTLVCFIVLKNRHMHTVTNMFILNLAVSDLLVGIFCMPTTLVDNLITGWPFDNATCKMSGLVQGMSVSASVFTLVAIAVERFRCIVHPFREKLTLRKALVTIAVIWALALLIMCPSAVTLTVTREEHHFMVDARNRSYPLYSCWEAWPEKGMRRVYTTVLFSHIYLAPLALIVVMYARIARKLCQAPGPAPGGEEAADPRASRRRARVVHMLVMVALFFTLSWLPLWALLLLIDYGQLSAPQLHLVTVYAFPFAHWLAFFNSSANPIIYGYFNENFRRGFQAAFRARLCPRPSGSHKEAYSERPGGLLHRRVFVVVRPSDSGLPSESGPSSGAPRPGRLPLRNGRVAHHGLPREGPGCSHLPLTIPAWDI
  
Inhibitor
Name:
BDBM50029097
Synonyms:
CHEMBL3361433
Type:
Small organic molecule
Emp. Form.:
C27H33N5O
Mol. Mass.:
443.5838
SMILES:
NC(=N)NCC(=O)NCC1(Cc2cccc3ccccc23)CCN(Cc2ccccc2)CC1
Structure:
Search PDB for entries with ligand similarity: