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Target
Myeloblastin
Ligand
BDBM50171289
Substrate
n/a
Meas. Tech.
ChEMBL_1442535 (CHEMBL3371659)
IC50
19230±n/a nM
Citation
 Budnjo, A; Narawane, S; Grauffel, C; Schillinger, AS; Fossen, T; Reuter, N; Haug, BE Reversible ketomethylene-based inhibitors of human neutrophil proteinase 3. J Med Chem 57:9396-408 (2014) [PubMed]  Article 
Target
Name:
Myeloblastin
Synonyms:
Leukocyte proteinase 3 | MBN | PRTN3 | PRTN3_HUMAN
Type:
PROTEIN
Mol. Mass.:
27816.30
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1463425
Residue:
256
Sequence:
MAHRPPSPALASVLLALLLSGAARAAEIVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLNDVLLIQLSSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFFCRPHNICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLRRVEAKGRP
  
Inhibitor
Name:
BDBM50171289
Synonyms:
Benzenemethanesulfonyl fluoride | CHEMBL190503 | PMSF | Phenylmethanesulfonyl fluoride | alpha-toluenesulfonyl fluoride | alpha-toluenesulphonyl fluoride | phenylmethylsulfonyl fluoride
Type:
Small organic molecule
Emp. Form.:
C7H7FO2S
Mol. Mass.:
174.193
SMILES:
FS(=O)(=O)Cc1ccccc1
Structure:
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