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Target
D(2) dopamine receptor
Ligand
BDBM50034799
Substrate
n/a
Meas. Tech.
ChEMBL_1441770 (CHEMBL3379420)
Ki
40±n/a nM
Citation
 Partyka, A; Chlon-Rzepa, G; Wasik, A; Jastrzebska-Wiesek, M; Bucki, A; Kolaczkowski, M; Satala, G; Bojarski, AJ; Wesolowska, A Antidepressant- and anxiolytic-like activity of 7-phenylpiperazinylalkyl-1,3-dimethyl-purine-2,6-dione derivatives with diversified 5-HT1A receptor functional profile. Bioorg Med Chem 23:212-21 (2014) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50034799
Synonyms:
CHEMBL3361001
Type:
Small organic molecule
Emp. Form.:
C22H30Cl2N6O2
Mol. Mass.:
481.419
SMILES:
Cl.Cn1c2ncn(CCCCCN3CCN(CC3)c3cccc(Cl)c3)c2c(=O)n(C)c1=O
Structure:
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