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Target
Forkhead box protein O3
Ligand
BDBM50349826
Substrate
n/a
Meas. Tech.
ChEMBL_1444407 (CHEMBL3372934)
Kd
1730000±n/a nM
Citation
 Park, HW; Cho, SY; Kim, HH; Yun, BS; Kim, JU; Lee, SJ; Park, J Enantioselective induction of SIRT1 gene by syringaresinol from Panax ginseng berry and Acanthopanax senticosus Harms stem. Bioorg Med Chem Lett 25:307-9 (2014) [PubMed]  Article 
Target
Name:
Forkhead box protein O3
Synonyms:
AF6q21 protein | FKHRL1 | FKHRL1 | FOXO3 | FOXO3A | FOXO3_HUMAN | Forkhead box protein O3 | Forkhead in rhabdomyosarcoma-like 1
Type:
PROTEIN
Mol. Mass.:
71261.26
Organism:
Homo sapiens (Human)
Description:
ChEMBL_101326
Residue:
673
Sequence:
MAEAPASPAPLSPLEVELDPEFEPQSRPRSCTWPLQRPELQASPAKPSGETAADSMIPEEEDDEDDEDGGGRAGSAMAIGGGGGSGTLGSGLLLEDSARVLAPGGQDPGSGPATAAGGLSGGTQALLQPQQPLPPPQPGAAGGSGQPRKCSSRRNAWGNLSYADLITRAIESSPDKRLTLSQIYEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQNEGTGKSSWWIINPDGGKSGKAPRRRAVSMDNSNKYTKSRGRAAKKKAALQTAPESADDSPSQLSKWPGSPTSRSSDELDAWTDFRSRTNSNASTVSGRLSPIMASTELDEVQDDDAPLSPMLYSSSASLSPSVSKPCTVELPRLTDMAGTMNLNDGLTENLMDDLLDNITLPPSQPSPTGGLMQRSSSFPYTTKGSGLGSPTSSFNSTVFGPSSLNSLRQSPMQTIQENKPATFSSMSHYGNQTLQDLLTSDSLSHSDVMMTQSDPLMSQASTAVSAQNSRRNVMLRNDPMMSFAAQPNQGSLVNQNLLHHQHQTQGALGGSRALSNSVSNMGLSESSSLGSAKHQQQSPVSQSMQTLSDSLSGSSLYSTSANLPVMGHEKFPSDLDLDMFNGSLECDMESIIRSELMDADGLDFNFDSLISTQNVVGLNVGNFTGAKQASSQSWVPG
  
Inhibitor
Name:
BDBM50349826
Synonyms:
SYRINGARESINOL
Type:
Small organic molecule
Emp. Form.:
C22H26O8
Mol. Mass.:
418.437
SMILES:
COc1cc(cc(OC)c1O)[C@H]1OC[C@H]2[C@@H]1CO[C@@H]2c1cc(OC)c(O)c(OC)c1 |r|
Structure:
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