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Target
Protein delta homolog 1
Ligand
BDBM50042942
Substrate
n/a
Meas. Tech.
ChEMBL_1444684 (CHEMBL3377246)
Ki
0.170000±n/a nM
Citation
 Abdel-Magid, AF Dual leucine zipper kinase inhibitors: potential treatments for neurodegenerative diseases. ACS Med Chem Lett 6:11-2 (2015) [PubMed]  Article 
Target
Name:
Protein delta homolog 1
Synonyms:
DLK | DLK-1 | DLK1 | DLK1_HUMAN | FA1 | Fetal antigen 1 | pG2
Type:
PROTEIN
Mol. Mass.:
41294.81
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1444684
Residue:
383
Sequence:
MTATEALLRVLLLLLAFGHSTYGAECFPACNPQNGFCEDDNVCRCQPGWQGPLCDQCVTSPGCLHGLCGEPGQCICTDGWDGELCDRDVRACSSAPCANNRTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRCPAGFIDKTCSRPVTNCASSPCQNGGTCLQHTQVSYECLCKPEFTGLTCVKKRALSPQQVTRLPSGYGLAYRLTPGVHELPVQQPEHRILKVSMKELNKKTPLLTEGQAICFTILGVLTSLVVLGTVGIVFLNKCETWVSNLRYNHMLRKKKNLLLQYNSGEDLAVNIIFPEKIDMTTFSKEAGDEEI
  
Inhibitor
Name:
BDBM50042942
Synonyms:
CHEMBL3355003
Type:
Small organic molecule
Emp. Form.:
C20H24F3N5
Mol. Mass.:
391.4333
SMILES:
CC(C)n1nc(cc1C1CCN(C)CC1)-c1cnc2[nH]cc(c2c1)C(F)(F)F
Structure:
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