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Target
Peroxisome proliferator-activated receptor alpha
Ligand
BDBM50044625
Substrate
n/a
Meas. Tech.
ChEMBL_1459834 (CHEMBL3371220)
Kd
1930±n/a nM
Citation
 Wu, C; Jia, Y; Lee, JH; Jun, HJ; Lee, HS; Hwang, KY; Lee, SJ trans-Caryophyllene is a natural agonistic ligand for peroxisome proliferator-activated receptor-a. Bioorg Med Chem Lett 24:3168-74 (2014) [PubMed]  Article 
Target
Name:
Peroxisome proliferator-activated receptor alpha
Synonyms:
NR1C1 | Nuclear receptor subfamily 1 group C member 1 | PPAR | PPAR alpha/gamma | PPAR-alpha | PPARA | PPARA_HUMAN | Peroxisome Proliferator-Activated Receptor alpha | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor alpha (PPAR alpha)
Type:
Enzyme
Mol. Mass.:
52222.08
Organism:
Human
Description:
Q07869
Residue:
468
Sequence:
MVDTESPLCPLSPLEAGDLESPLSEEFLQEMGNIQEISQSIGEDSSGSFGFTEYQYLGSCPGSDGSVITDTLSPASSPSSVTYPVVPGSVDESPSGALNIECRICGDKASGYHYGVHACEGCKGFFRRTIRLKLVYDKCDRSCKIQKKNRNKCQYCRFHKCLSVGMSHNAIRFGRMPRSEKAKLKAEILTCEHDIEDSETADLKSLAKRIYEAYLKNFNMNKVKARVILSGKASNNPPFVIHDMETLCMAEKTLVAKLVANGIQNKEAEVRIFHCCQCTSVETVTELTEFAKAIPGFANLDLNDQVTLLKYGVYEAIFAMLSSVMNKDGMLVAYGNGFITREFLKSLRKPFCDIMEPKFDFAMKFNALELDDSDISLFVAAIICCGDRPGLLNVGHIEKMQEGIVHVLRLHLQSNHPDDIFLFPKLLQKMADLRQLVTEHAQLVQIIKKTESDAALHPLLQEIYRDMY
  
Inhibitor
Name:
BDBM50044625
Synonyms:
CHEMBL3360190
Type:
Small organic molecule
Emp. Form.:
C14H22
Mol. Mass.:
190.3245
SMILES:
[H][C@]12CC(C)(C)[C@]1([H])CC\C=C\CCC2=C |r,t:11|
Structure:
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