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Target
G-protein coupled estrogen receptor 1
Ligand
BDBM50044849
Substrate
n/a
Meas. Tech.
ChEMBL_1455302 (CHEMBL3362666)
EC50
<50119±n/a nM
Citation
 Sparks, SM; Chen, G; Collins, JL; Danger, D; Dock, ST; Jayawickreme, C; Jenkinson, S; Laudeman, C; Leesnitzer, MA; Liang, X; Maloney, P; McCoy, DC; Moncol, D; Rash, V; Rimele, T; Vulimiri, P; Way, JM; Ross, S Identification of diarylsulfonamides as agonists of the free fatty acid receptor 4 (FFA4/GPR120). Bioorg Med Chem Lett 24:3100-3 (2014) [PubMed]  Article 
Target
Name:
G-protein coupled estrogen receptor 1
Synonyms:
Chemoattractant receptor-like 2 | Cmkrl2 | Cmkrl2 | G protein-coupled estrogen receptor 1 | G-protein coupled estrogen receptor 1 | G-protein coupled receptor 30 | G-protein coupled receptor 41 | GPER1_RAT | Gper | Gper1 | Gpr30 | Gpr41 | Membrane estrogen receptor | mER
Type:
PROTEIN
Mol. Mass.:
42266.72
Organism:
Rattus norvegicus
Description:
ChEMBL_109432
Residue:
375
Sequence:
MAATTPAQDVGVEIYLGPVWPAPSNSTPLALNLSLALREDAPGNLTGDLSEHQQYVIALFLSCLYTIFLFPIGFVGNILILVVNISFREKMTIPDLYFINLAAADLILVADSLIEVFNLDEQYYDIAVLCTFMSLFLQINMYSSVFFLTWMSFDRYLALAKAMRCGLFRTKHHARLSCGLIWMASVSATLVPFTAVHLRHTEEACFCFADVREVQWLEVTLGFIVPFAIIGLCYSLIVRALIRAHRHRGLRPRRQKALRMIFAVVLVFFICWLPENVFISVHLLQWAQPGDTPCKQSFRHAYPLTGHIVNLAAFSNSCLSPLIYSFLGETFRDKLRLYVAQKTSLPALNRFCHATLKAVIPDSTEQSDVKFSSAV
  
Inhibitor
Name:
BDBM50044849
Synonyms:
CHEMBL3311308
Type:
Small organic molecule
Emp. Form.:
C16H19NO3S
Mol. Mass.:
305.392
SMILES:
COc1ccc(cc1)S(=O)(=O)Nc1c(C)cc(C)cc1C
Structure:
Search PDB for entries with ligand similarity: