Reaction Details Report a problem with these data
Target
Oxoeicosanoid receptor 1
Ligand
BDBM50046281
Substrate
n/a
Meas. Tech.
ChEMBL_1447591 (CHEMBL3373786)
IC50
460±n/a nM
Citation
 Gore, V; Chourey, S; Ye, Q; Patel, P; Ouedraogo, Y; Gravel, S; Powell, WS; Rokach, J Base-dependent formation of cis and trans olefins and their application in the synthesis of 5-oxo-ETE receptor antagonists. Bioorg Med Chem Lett 24:3385-8 (2014) [PubMed]  Article 
Target
Name:
Oxoeicosanoid receptor 1
Synonyms:
5-oxo-ETE G-protein coupled receptor | G-protein coupled receptor 170 | G-protein coupled receptor R527 | G-protein coupled receptor TG1019 | GPR170 | OXER1 | OXER1_HUMAN | Oxoeicosanoid receptor 1 | TG 1019 | TG1019
Type:
Enzyme Catalytic Domain
Mol. Mass.:
45833.20
Organism:
Homo sapiens (Human)
Description:
TG 1019 0 HUMAN::Q8TDS5
Residue:
423
Sequence:
MLCHRGGQLIVPIIPLCPEHSCRGRRLQNLLSGPWPKQPMELHNLSSPSPSLSSSVLPPSFSPSPSSAPSAFTTVGGSSGGPCHPTSSSLVSAFLAPILALEFVLGLVGNSLALFIFCIHTRPWTSNTVFLVSLVAADFLLISNLPLRVDYYLLHETWRFGAAACKVNLFMLSTNRTASVVFLTAIALNRYLKVVQPHHVLSRASVGAAARVAGGLWVGILLLNGHLLLSTFSGPSCLSYRVGTKPSASLRWHQALYLLEFFLPLALILFAIVSIGLTIRNRGLGGQAGPQRAMRVLAMVVAVYTICFLPSIIFGMASMVAFWLSACRSLDLCTQLFHGSLAFTYLNSVLDPVLYCFSSPNFLHQSRALLGLTRGRQGPVSDESSYQPSRQWRYREASRKAEAIGKLKVQGEVSLEKEGSSQG
  
Inhibitor
Name:
BDBM50046281
Synonyms:
CHEMBL3311230
Type:
Small organic molecule
Emp. Form.:
C20H24ClNO3
Mol. Mass.:
361.862
SMILES:
CCCC\C=C/c1cc2ccc(Cl)cc2n1C(=O)CC(C)CC(O)=O
Structure:
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