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Target
Reverse transcriptase
Ligand
BDBM50046721
Substrate
n/a
Meas. Tech.
ChEMBL_1451901 (CHEMBL3363071)
IC50
1410±n/a nM
Citation
 Chen, H; Hao, L; Zhu, M; Yang, T; Wei, S; Qin, Z; Zhang, P; Li, X Synthesis of bi-/tricyclic azasugars fused thiazinan-4-one and their HIV-RT inhibitory activity. Bioorg Med Chem Lett 24:3426-9 (2014) [PubMed]  Article 
Target
Name:
Reverse transcriptase
Synonyms:
n/a
Type:
Protein
Mol. Mass.:
29598.37
Organism:
Human immunodeficiency virus 1
Description:
Q9WKE8
Residue:
254
Sequence:
PISPITVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIEKIGPENPYNTPVFAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVN
  
Inhibitor
Name:
BDBM50046721
Synonyms:
CHEMBL3310876
Type:
Small organic molecule
Emp. Form.:
C9H15NO5S
Mol. Mass.:
249.284
SMILES:
[H][C@]12SCCC(=O)N1[C@H](CO)[C@@H](O)[C@H](O)[C@@H]2O |r|
Structure:
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