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Target
Aromatase
Ligand
BDBM50048707
Substrate
n/a
Meas. Tech.
ChEMBL_1451081 (CHEMBL3366858)
IC50
34400±n/a nM
Citation
 Parrish, SM; Yoshida, WY; Kondratyuk, TP; Park, EJ; Pezzuto, JM; Kelly, M; Williams, PG Spongiapyridine and related spongians isolated from an Indonesian Spongia sp. J Nat Prod 77:1644-9 (2014) [PubMed]  Article 
Target
Name:
Aromatase
Synonyms:
ARO1 | Aromatase | CP19A_HUMAN | CYAR | CYP19 | CYP19A1 | CYPXIX | Cytochrome P-450AROM | Cytochrome P450 19A1 | Cytochrome P450 2C19 | Cytochrome P450-C19 (CYP19) | Estrogen synthetase | FL cytokine receptor precursor | P-450AROM
Type:
Enzyme
Mol. Mass.:
57888.92
Organism:
Homo sapiens (Human)
Description:
P11511
Residue:
503
Sequence:
MVLEMLNPIHYNITSIVPEAMPAATMPVLLLTGLFLLVWNYEGTSSIPGPGYCMGIGPLISHGRFLWMGIGSACNYYNRVYGEFMRVWISGEETLIISKSSSMFHIMKHNHYSSRFGSKLGLQCIGMHEKGIIFNNNPELWKTTRPFFMKALSGPGLVRMVTVCAESLKTHLDRLEEVTNESGYVDVLTLLRRVMLDTSNTLFLRIPLDESAIVVKIQGYFDAWQALLIKPDIFFKISWLYKKYEKSVKDLKDAIEVLIAEKRRRISTEEKLEECMDFATELILAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIGRMHRLEFFPKPNEFTLENFAKNVPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRFHVKTLQGQCVESIQKIHDLSLHPDETKNMLEMIFTPRNSDRCLEH
  
Inhibitor
Name:
BDBM50048707
Synonyms:
CHEMBL3315157
Type:
Small organic molecule
Emp. Form.:
C19H24O5
Mol. Mass.:
332.3909
SMILES:
[H][C@]12CCc3cocc3[C@]1(CO)CCC1(O)C(C)=C(O)C(=O)C[C@]21C |r,t:19|
Structure:
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