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Target
Serine racemase
Ligand
BDBM50055465
Substrate
n/a
Meas. Tech.
ChEMBL_1450503 (CHEMBL3380621)
IC50
520000±n/a nM
Citation
 Mori, H; Wada, R; Li, J; Ishimoto, T; Mizuguchi, M; Obita, T; Gouda, H; Hirono, S; Toyooka, N In silico and pharmacological screenings identify novel serine racemase inhibitors. Bioorg Med Chem Lett 24:3732-5 (2014) [PubMed]  Article 
Target
Name:
Serine racemase
Synonyms:
SRR | SRR_HUMAN
Type:
PROTEIN
Mol. Mass.:
36565.80
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1516972
Residue:
340
Sequence:
MCAQYCISFADVEKAHINIRDSIHLTPVLTSSILNQLTGRNLFFKCELFQKTGSFKIRGALNAVRSLVPDALERKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPDCKKLAIQAYGASIVYCEPSDESRENVAKRVTEETEGIMVHPNQEPAVIAGQGTIALEVLNQVPLVDALVVPVGGGGMLAGIAITVKALKPSVKVYAAEPSNADDCYQSKLKGKLMPNLYPPETIADGVKSSIGLNTWPIIRDLVDDIFTVTEDEIKCATQLVWERMKLLIEPTAGVGVAAVLSQHFQTVSPEVKNICIVLSGGNVDLTSSITWVKQAERPASYQSVSV
  
Inhibitor
Name:
BDBM50055465
Synonyms:
CHEMBL3317754
Type:
Small organic molecule
Emp. Form.:
C16H14BrFN2O3
Mol. Mass.:
381.196
SMILES:
Fc1ccc(OCC(=O)NCC(=O)Nc2ccc(Br)cc2)cc1
Structure:
Search PDB for entries with ligand similarity: