Reaction Details Report a problem with these data
Target
Protein tyrosine phosphatase type IVA 2
Ligand
BDBM50059142
Substrate
n/a
Meas. Tech.
ChEMBL_1461023 (CHEMBL3395081)
IC50
109200±n/a nM
Citation
 Hoeger, B; Diether, M; Ballester, PJ; Köhn, M Biochemical evaluation of virtual screening methods reveals a cell-active inhibitor of the cancer-promoting phosphatases of regenerating liver. Eur J Med Chem 88:89-100 (2014) [PubMed]  Article 
Target
Name:
Protein tyrosine phosphatase type IVA 2
Synonyms:
PRL2 | PTP4A2 | PTPCAAX2 | TP4A2_HUMAN
Type:
PROTEIN
Mol. Mass.:
19133.04
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1461023
Residue:
167
Sequence:
MNRPAPVEISYENMRFLITHNPTNATLNKFTEELKKYGVTTLVRVCDATYDKAPVEKEGIHVLDWPFDDGAPPPNQIVDDWLNLLKTKFREEPGCCVAVHCVAGLGRAPVLVALALIECGMKYEDAVQFIRQKRRGAFNSKQLLYLEKYRPKMRLRFRDTNGHCCVQ
  
Inhibitor
Name:
BDBM50059142
Synonyms:
CHEMBL3393150
Type:
Small organic molecule
Emp. Form.:
C12H9Br2NO3
Mol. Mass.:
375.013
SMILES:
CCOC(=O)C(=C\c1cc(Br)c(O)c(Br)c1)\C#N
Structure:
Search PDB for entries with ligand similarity: