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Target
Ubiquitin-like domain-containing CTD phosphatase 1
Ligand
BDBM26193
Substrate
n/a
Meas. Tech.
ChEMBL_1476058 (CHEMBL3428554)
pH
6±n/a
IC50
66000000±n/a nM
Comments
extracted
Citation
 He, Y; Guo, X; Yu, ZH; Wu, L; Gunawan, AM; Zhang, Y; Dixon, JE; Zhang, ZY A potent and selective inhibitor for the UBLCP1 proteasome phosphatase. Bioorg Med Chem 23:2798-809 (2015) [PubMed]  Article 
Target
Name:
Ubiquitin-like domain-containing CTD phosphatase 1
Synonyms:
Nuclear proteasome inhibitor UBLCP1 | UBCP1_HUMAN | UBLCP1 | Ubiquitin-like domain-containing CTD phosphatase 1
Type:
Enzyme
Mol. Mass.:
36803.71
Organism:
Homo sapiens (Human)
Description:
Q8WVY7
Residue:
318
Sequence:
MALPIIVKWGGQEYSVTTLSEDDTVLDLKQFLKTLTGVLPERQKLLGLKVKGKPAENDVKLGALKLKPNTKIMMMGTREESLEDVLGPPPDNDDVVNDFDIEDEVVEVENREENLLKISRRVKEYKVEILNPPREGKKLLVLDVDYTLFDHRSCAETGVELMRPYLHEFLTSAYEDYDIVIWSATNMKWIEAKMKELGVSTNANYKITFMLDSAAMITVHTPRRGLIDVKPLGVIWGKFSEFYSKKNTIMFDDIGRNFLMNPQNGLKIRPFMKAHLNRDKDKELLKLTQYLKEIAKLDDFLDLNHKYWERYLSKKQGQ
  
Inhibitor
Name:
BDBM26193
Synonyms:
2-Hydroxybenzoate, I | 2-hydroxybenzoic acid | CHEMBL424 | phenol derivative, 7 | salicylic acid
Type:
Small organic molecule
Emp. Form.:
C7H6O3
Mol. Mass.:
138.1207
SMILES:
OC(=O)c1ccccc1O
Structure:
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