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Target
Inhibin beta A chain
Ligand
BDBM50095126
Substrate
n/a
Meas. Tech.
ChEMBL_1503623 (CHEMBL3591943)
IC50
4180±n/a nM
Citation
 Zhu, J; Mishra, RK; Schiltz, GE; Makanji, Y; Scheidt, KA; Mazar, AP; Woodruff, TK Virtual High-Throughput Screening To Identify Novel Activin Antagonists. J Med Chem 58:5637-48 (2015) [PubMed]  Article 
Target
Name:
Inhibin beta A chain
Synonyms:
Activin beta-A chain | INHBA_MOUSE | Inhba | Inhibin beta A chain
Type:
PROTEIN
Mol. Mass.:
47403.32
Organism:
Mus musculus
Description:
ChEMBL_109823
Residue:
424
Sequence:
MPLLWLRGFLLASCWIIVRSSPTPGSEGHGSAPDCPSCALATLPKDGPNSQPEMVEAVKKHILNMLHLKKRPDVTQPVPKAALLNAIRKLHVGKVGENGYVEIEDDIGRRAEMNELMEQTSEIITFAESGTARKTLHFEISKEGSDLSVVERAEVWLFLKVPKANRTRTKVTIRLFQQQKHPQGSLDTGDEAEEMGLKGERSELLLSEKVVDARKSTWHIFPVSSSIQRLLDQGKSSLDVRIACEQCQESGASLVLLGKKKKKEVDGDGKKKDGSDGGLEEEKEQSHRPFLMLQARQSEDHPHRRRRRGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS
  
Inhibitor
Name:
BDBM50095126
Synonyms:
CHEMBL3589514
Type:
Small organic molecule
Emp. Form.:
C23H33N3O4
Mol. Mass.:
415.5258
SMILES:
COc1ccc(OC[C@@H](O)CN2CCC(O)CC2)c(CNCCc2cccnc2)c1 |r|
Structure:
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