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Target
Inhibin beta A chain
Ligand
BDBM50095127
Substrate
n/a
Meas. Tech.
ChEMBL_1503623 (CHEMBL3591943)
IC50
100000±n/a nM
Citation
 Zhu, J; Mishra, RK; Schiltz, GE; Makanji, Y; Scheidt, KA; Mazar, AP; Woodruff, TK Virtual High-Throughput Screening To Identify Novel Activin Antagonists. J Med Chem 58:5637-48 (2015) [PubMed]  Article 
Target
Name:
Inhibin beta A chain
Synonyms:
Activin beta-A chain | INHBA_MOUSE | Inhba | Inhibin beta A chain
Type:
PROTEIN
Mol. Mass.:
47403.32
Organism:
Mus musculus
Description:
ChEMBL_109823
Residue:
424
Sequence:
MPLLWLRGFLLASCWIIVRSSPTPGSEGHGSAPDCPSCALATLPKDGPNSQPEMVEAVKKHILNMLHLKKRPDVTQPVPKAALLNAIRKLHVGKVGENGYVEIEDDIGRRAEMNELMEQTSEIITFAESGTARKTLHFEISKEGSDLSVVERAEVWLFLKVPKANRTRTKVTIRLFQQQKHPQGSLDTGDEAEEMGLKGERSELLLSEKVVDARKSTWHIFPVSSSIQRLLDQGKSSLDVRIACEQCQESGASLVLLGKKKKKEVDGDGKKKDGSDGGLEEEKEQSHRPFLMLQARQSEDHPHRRRRRGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS
  
Inhibitor
Name:
BDBM50095127
Synonyms:
CHEMBL3589515
Type:
Small organic molecule
Emp. Form.:
C28H25N3O6
Mol. Mass.:
499.5146
SMILES:
OC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](Cc1ccc2OCOc2c1)NC(=O)c1ccccc1 |r|
Structure:
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