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Target
Heat shock protein beta-1
Ligand
BDBM50097558
Substrate
n/a
Meas. Tech.
ChEMBL_1500622 (CHEMBL3587752)
IC50
200±n/a nM
Citation
 Fossa, P; Cichero, E In silico evaluation of human small heat shock protein HSP27: homology modeling, mutation analyses and docking studies. Bioorg Med Chem 23:3215-20 (2015) [PubMed]  Article 
Target
Name:
Heat shock protein beta-1
Synonyms:
HSP27 | HSP28 | HSPB1 | HSPB1_HUMAN
Type:
PROTEIN
Mol. Mass.:
22781.73
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1500622
Residue:
205
Sequence:
MTERRVPFSLLRGPSWDPFRDWYPHSRLFDQAFGLPRLPEEWSQWLGGSSWPGYVRPLPPAAIESPAVAAPAYSRALSRQLSSGVSEIRHTADRWRVSLDVNHFAPDELTVKTKDGVVEITGKHEERQDEHGYISRCFTRKYTLPPGVDPTQVSSSLSPEGTLTVEAPMPKLATQSNEITIPVTFESRAQLGGPEAAKSDETAAK
  
Inhibitor
Name:
BDBM50097558
Synonyms:
CHEMBL1935538 | NSC-751382
Type:
Small organic molecule
Emp. Form.:
C25H26N2O6S
Mol. Mass.:
482.549
SMILES:
CN(c1ccc(NC(=O)c2ccc3OCOc3c2)cc1OCc1cc(C)ccc1C)S(C)(=O)=O
Structure:
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