Reaction Details Report a problem with these data
Target
D(3) dopamine receptor
Ligand
BDBM50097670
Substrate
n/a
Meas. Tech.
ChEMBL_1504485 (CHEMBL3590825)
EC50
6.1±n/a nM
Citation
 Bartuschat, AL; Schellhorn, T; Hübner, H; Gmeiner, P; Heinrich, MR Fluoro-substituted phenylazocarboxamides: Dopaminergic behavior and N-arylating properties for irreversible binding. Bioorg Med Chem 23:3938-47 (2015) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50097670
Synonyms:
CHEMBL3590082
Type:
Small organic molecule
Emp. Form.:
C23H28F2N4O
Mol. Mass.:
414.4914
SMILES:
CCCN(CCCCNC(=O)\N=N\c1ccc(F)c(F)c1)C1Cc2ccccc2C1
Structure:
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