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Target
Carbonic anhydrase 1
Ligand
BDBM50098587
Substrate
n/a
Meas. Tech.
ChEMBL_1446410 (CHEMBL3375524)
Ki
200000±n/a nM
Citation
 Del Prete, S; Vullo, D; Fisher, GM; Andrews, KT; Poulsen, SA; Capasso, C; Supuran, CT Discovery of a new family of carbonic anhydrases in the malaria pathogen Plasmodium falciparum--theż-carbonic anhydrases. Bioorg Med Chem Lett 24:4389-96 (2014) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 1
Synonyms:
CA-I | CA1 | CAB | CAH1_HUMAN | Carbonate dehydratase I | Carbonic anhydrase | Carbonic anhydrase 1 (CA I) | Carbonic anhydrase 1 (CA-I) | Carbonic anhydrase 1 (Recombinant CA I) | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase B | Carbonic anhydrase I | Carbonic anhydrase I (CA I) | Carbonic anhydrase I (CA-I) | Carbonic anhydrase I (CAI) | Carbonic anhydrase I (hCA I) | Carbonic anhydrase isoenzyme I (hCA I) | hCA
Type:
Enzyme
Mol. Mass.:
28873.37
Organism:
Homo sapiens (Human)
Description:
P00915
Residue:
261
Sequence:
MASPDWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEIINVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELHVAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNFDPSTLLPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAVPMQHNNRPTQPLKGRTVRASF
  
Inhibitor
Name:
BDBM50098587
Synonyms:
CHEBI:30952 | Sodium Rhodanate | Sodium Sulfocyanate | Thiocyanate Sodium | Thiocyanic Acid
Type:
Small organic molecule
Emp. Form.:
CNNaS
Mol. Mass.:
81.072
SMILES:
[Na+].[S-]C#N
Structure:
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