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Target
5-hydroxytryptamine receptor 1A
Ligand
BDBM10452
Substrate
n/a
Meas. Tech.
ChEMBL_1436288 (CHEMBL3388369)
Ki
832±n/a nM
Citation
 Chen, J; Campbell, AP; Urmi, KF; Wakelin, LP; Denny, WA; Griffith, R; Finch, AM Human alpha1-adrenoceptor subtype selectivity of substituted homobivalent 4-aminoquinolines. Bioorg Med Chem 22:5910-6 (2014) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 1A
Synonyms:
5-HT-1A | 5-HT1A | 5-hydroxytryptamine receptor 1A (5-HT-1A) | 5HT1A_HUMAN | ADRB2RL1 | ADRBRL1 | Dopamine D2 receptor and serotonin 1a receptor | G-21 | HTR1A | Serotonin receptor 1A
Type:
n/a
Mol. Mass.:
46122.49
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
422
Sequence:
MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ
  
Inhibitor
Name:
BDBM10452
Synonyms:
Bivalent 4-Aminoquinoline 9f | N,N-di-4-Quinolyl-1,7-diaminoheptane dihydrochloride | N-[7-(quinolin-4-ylamino)heptyl]quinolin-4-amine dihydrochloride
Type:
Small organic molecule
Emp. Form.:
C25H28N4
Mol. Mass.:
384.5166
SMILES:
C(CCCNc1ccnc2ccccc12)CCCNc1ccnc2ccccc12
Structure:
Search PDB for entries with ligand similarity: