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Target
Cannabinoid receptor 1
Ligand
BDBM50116912
Substrate
n/a
Meas. Tech.
ChEMBL_1516108 (CHEMBL3615751)
Ki
>5000±n/a nM
Citation
 Ragusa, G; Gómez-Cañas, M; Morales, P; Hurst, DP; Deligia, F; Pazos, R; Pinna, GA; Fernández-Ruiz, J; Goya, P; Reggio, PH; Jagerovic, N; García-Arencibia, M; Murineddu, G Synthesis, pharmacological evaluation and docking studies of pyrrole structure-based CB2 receptor antagonists. Eur J Med Chem 101:651-67 (2015) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50116912
Synonyms:
CHEMBL3613104
Type:
Small organic molecule
Emp. Form.:
C30H37ClN2O
Mol. Mass.:
477.081
SMILES:
CC(C)[C@H]1CC[C@H](C)C[C@@H]1NC(=O)c1cc(-c2ccc(Cl)c(C)c2)n(Cc2ccc(C)cc2)c1 |r|
Structure:
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