Reaction Details Report a problem with these data
Target
Free fatty acid receptor 1
Ligand
BDBM50129141
Substrate
n/a
Meas. Tech.
ChEMBL_1523192 (CHEMBL3632223)
EC50
110±n/a nM
Citation
 Li, Z; Wang, X; Xu, X; Yang, J; Xia, W; Zhou, X; Huang, W; Qian, H Design, synthesis and biological activity of phenoxyacetic acid derivatives as novel free fatty acid receptor 1 agonists. Bioorg Med Chem 23:7158-64 (2015) [PubMed]  Article 
Target
Name:
Free fatty acid receptor 1
Synonyms:
FFAR1 | FFAR1_HUMAN | G-protein Coupled Receptor 40 | GPR40
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
31473.32
Organism:
Homo sapiens (Human)
Description:
O14842
Residue:
300
Sequence:
MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAGPARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
  
Inhibitor
Name:
BDBM50129141
Synonyms:
CHEMBL3629046
Type:
Small organic molecule
Emp. Form.:
C26H27FO6
Mol. Mass.:
454.4874
SMILES:
Cc1cc(OCCCO)cc(C)c1-c1cccc(COc2ccc(OCC(O)=O)c(F)c2)c1
Structure:
Search PDB for entries with ligand similarity: