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Target
Kappa-type opioid receptor
Ligand
BDBM50140037
Substrate
n/a
Meas. Tech.
ChEBML_1554327
Ki
>10000±n/a nM
Citation
 Li, Y; Cazares, M; Wu, J; Houghten, RA; Toll, L; Dooley, C Potentµ-Opioid Receptor Agonists from Cyclic Peptides Tyr-c[D-Lys-Xxx-Tyr-Gly]: Synthesis, Biological, and Structural Evaluation. J Med Chem 59:1239-45 (2016) [PubMed]  Article 
Target
Name:
Kappa-type opioid receptor
Synonyms:
Kappa Opioid Receptor | OPIATE Kappa | OPRK1 | OPRK_CAVPO | Opiate Kappa 1 | mu/kappa opioid receptor
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42744.99
Organism:
Cavia porcellus (domestic guinea pig)
Description:
P41144
Residue:
380
Sequence:
MGRRRQGPAQPASELPARNACLLPNGSAWLPGWAEPDGNGSAGPQDEQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIILGGTKVREDVDIIECSLQFPDDDYSWWDLFMKICVFVFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFIICWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPIKMRMERQSTSRVRNTVQDPAYMRNVDGVNKPV
  
Inhibitor
Name:
BDBM50140037
Synonyms:
CHEMBL3763452
Type:
Small organic molecule
Emp. Form.:
C35H41N5O7
Mol. Mass.:
643.7293
SMILES:
[H][C@@]12Cc3ccc(O)cc3CN1[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)NCCCC[C@@H](NC2=O)C(=O)[C@@H](N)Cc1ccc(O)cc1 |r|
Structure:
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