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Target
Mu-type opioid receptor
Ligand
BDBM50142693
Substrate
n/a
Meas. Tech.
ChEMBL_1552638 (CHEMBL3762577)
Ki
0.380000±n/a nM
Citation
 Turnaturi, R; Aricò, G; Ronsisvalle, G; Parenti, C; Pasquinucci, L Multitarget opioid ligands in pain relief: New players in an old game. Eur J Med Chem 108:211-28 (2016) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50142693
Synonyms:
CHEMBL3759238
Type:
Small organic molecule
Emp. Form.:
C21H27NO3
Mol. Mass.:
341.444
SMILES:
[H][C@@]12CCCC[C@@]11CCN(CC3CCCO3)[C@]2([H])C(=O)c2ccc(O)cc12 |r,TLB:25:26:1:7.9.8,19:18:1:7.9.8,THB:10:9:20.26.18:1,2:1:20.26.18:7.9.8|
Structure:
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