Reaction Details Report a problem with these data
Target
Free fatty acid receptor 1
Ligand
BDBM50143016
Substrate
n/a
Meas. Tech.
ChEMBL_1553061 (CHEMBL3760345)
EC50
23120±n/a nM
Citation
 Darwish, KM; Salama, I; Mostafa, S; Gomaa, MS; Helal, MA Design, synthesis, and biological evaluation of novel thiazolidinediones as PPAR¿/FFAR1 dual agonists. Eur J Med Chem 109:157-72 (2016) [PubMed]  Article 
Target
Name:
Free fatty acid receptor 1
Synonyms:
FFAR1 | FFAR1_HUMAN | G-protein Coupled Receptor 40 | GPR40
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
31473.32
Organism:
Homo sapiens (Human)
Description:
O14842
Residue:
300
Sequence:
MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAGPARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
  
Inhibitor
Name:
BDBM50143016
Synonyms:
CHEMBL3759133
Type:
Small organic molecule
Emp. Form.:
C17H14BrNO3S
Mol. Mass.:
392.267
SMILES:
Brc1ccc(COc2ccc(CC3SC(=O)NC3=O)cc2)cc1
Structure:
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