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Target
Prostaglandin G/H synthase 1
Ligand
BDBM50147007
Substrate
n/a
Meas. Tech.
ChEBML_1554539
IC50
421200±n/a nM
Citation
 Aldawsari, FS; Aguiar, RP; Wiirzler, LA; Aguayo-Ortiz, R; Aljuhani, N; Cuman, RK; Medina-Franco, JL; Siraki, AG; Velázquez-Martínez, CA Anti-inflammatory and antioxidant properties of a novel resveratrol-salicylate hybrid analog. Bioorg Med Chem Lett 26:1411-5 (2016) [PubMed]  Article 
Target
Name:
Prostaglandin G/H synthase 1
Synonyms:
COX1 | Cyclooxygenase-1 | Cyclooxygenase-1 (COX-1) | PGH1_SHEEP | PTGS1 | Prostaglandin G/H synthase (cyclooxygenase)
Type:
Protein
Mol. Mass.:
68868.60
Organism:
Ovis aries (Sheep)
Description:
n/a
Residue:
600
Sequence:
MSRQSISLRFPLLLLLLSPSPVFSADPGAPAPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPEIWTWLRTTLRPSPSFIHFLLTHGRWLWDFVNATFIRDTLMRLVLTVRSNLIPSPPTYNIAHDYISWESFSNVSYYTRILPSVPRDCPTPMDTKGKKQLPDAEFLSRRFLLRRKFIPDPQSTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQMLNGEVYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATIWLREHNRVCDLLKAEHPTWGDEQLFQTARLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGAQFQYRNRIAMEFNQLYHWHPLMPDSFRVGPQDYSYEQFLFNTSMLVDYGVEALVDAFSRQPAGRIGGGRNIDHHILHVAVDVIKESRVLRLQPFNEYRKRFGMKPYTSFQELTGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEMGAPFSLKGLLGNPICSPEYWKASTFGGEVGFNLVKTATLKKLVCLNTKTCPYVSFHVPDPRQEDRPGVERPPTEL
  
Inhibitor
Name:
BDBM50147007
Synonyms:
CHEMBL1095380
Type:
Small organic molecule
Emp. Form.:
C15H12O4
Mol. Mass.:
256.2534
SMILES:
OC(=O)c1cc(\C=C\c2ccc(O)cc2)ccc1O
Structure:
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