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Target
Chromobox protein homolog 7
Ligand
BDBM50157430
Substrate
n/a
Meas. Tech.
ChEMBL_1565742 (CHEMBL3782540)
IC50
1700±n/a nM
Citation
 Milosevich, N; Gignac, MC; McFarlane, J; Simhadri, C; Horvath, S; Daze, KD; Croft, CS; Dheri, A; Quon, TT; Douglas, SF; Wulff, JE; Paci, I; Hof, F Selective Inhibition of CBX6: A Methyllysine Reader Protein in the Polycomb Family. ACS Med Chem Lett 7:139-44 (2016) [PubMed]  Article 
Target
Name:
Chromobox protein homolog 7
Synonyms:
CBX7 | CBX7_HUMAN | Chromobox protein homolog 7 | Chromobox protein homolog 7 (CBX7)
Type:
Protein
Mol. Mass.:
28351.76
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
251
Sequence:
MELSAIGEQVFAVESIRKKRVRKGKVEYLVKWKGWPPKYSTWEPEEHILDPRLVMAYEEKEERDRASGYRKRGPKPKRLLLQRLYSMDLRSSHKAKGKEKLCFSLTCPLGSGSPEGVVKAGAPELVDKGPLVPTLPFPLRKPRKAHKYLRLSRKKFPPRGPNLESHSHRRELFLQEPPAPDVLQAAGEWEPAAQPPEEEADADLAEGPPPWTPALPSSEVTVTDITANSITVTFREAQAAEGFFRDRSGKF
  
Inhibitor
Name:
BDBM50157430
Synonyms:
CHEMBL3781271
Type:
Small organic molecule
Emp. Form.:
C40H53BrN7O8
Mol. Mass.:
839.794
SMILES:
C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(Br)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCC[N+](C)(C)C)C(=O)N[C@@H](CO)C(N)=O |r|
Structure:
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