Reaction Details Report a problem with these data
Target
Similar to alpha-tubulin isoform 1
Ligand
BDBM50156464
Substrate
n/a
Meas. Tech.
ChEMBL_1572217 (CHEMBL3795663)
IC50
150±n/a nM
Citation
 Driowya, M; Leclercq, J; Verones, V; Barczyk, A; Lecoeur, M; Renault, N; Flouquet, N; Ghinet, A; Berthelot, P; Lebegue, N Synthesis of triazoloquinazolinone based compounds as tubulin polymerization inhibitors and vascular disrupting agents. Eur J Med Chem 115:393-405 (2016) [PubMed]  Article 
Target
Name:
Similar to alpha-tubulin isoform 1
Synonyms:
Similar to alpha-tubulin isoform 1
Type:
PROTEIN
Mol. Mass.:
10383.05
Organism:
Bos taurus
Description:
ChEMBL_104716
Residue:
99
Sequence:
CVSASPSTLARLVSRSAMPAGSSTAWNTAFSPMARCQVTKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRSSSTLSSSSQAKKMP
  
Inhibitor
Name:
BDBM50156464
Synonyms:
CHEMBL3793652
Type:
Small organic molecule
Emp. Form.:
C17H14N4O3
Mol. Mass.:
322.3181
SMILES:
COc1ccc(cc1O)-c1nnc2n(C)c(=O)c3ccccc3n12
Structure:
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