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Target
Prostaglandin E2 receptor EP1 subtype
Ligand
BDBM50156528
Substrate
n/a
Meas. Tech.
ChEMBL_1570608 (CHEMBL3794976)
EC50
>10000±n/a nM
Citation
 Ogawa, S; Watanabe, T; Moriyuki, K; Goto, Y; Yamane, S; Watanabe, A; Tsuboi, K; Kinoshita, A; Okada, T; Takeda, H; Tani, K; Maruyama, T Structural optimization and structure-functional selectivity relationship studies of G protein-biased EP2 receptor agonists. Bioorg Med Chem Lett 26:2446-9 (2016) [PubMed]  Article 
Target
Name:
Prostaglandin E2 receptor EP1 subtype
Synonyms:
PE2R1_HUMAN | PGE receptor, EP1 subtype | PTGER1 | Prostaglandin E2 receptor | Prostaglandin E2 receptor EP1 subtype | Prostaglandin E2 receptor EP1 subtype (EP1) | Prostanoid EP1 receptor
Type:
Enzyme
Mol. Mass.:
41834.57
Organism:
Homo sapiens (Human)
Description:
P34995
Residue:
402
Sequence:
MSPCGPLNLSLAGEATTCAAPWVPNTSAVPPSGASPALPIFSMTLGAVSNLLALALLAQAAGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVALAVALLPLARVGRYELQYPGTWCFIGLGPPGGWRQALLAGLFASLGLVALLAALVCNTLSGLALLRARWRRRSRRPPPASGPDSRRRWGAHGPRSASASSASSIASASTFFGGSRSSGSARRARAHDVEMVGQLVGIMVVSCICWSPMLVLVALAVGGWSSTSLQRPLFLAVRLASWNQILDPWVYILLRQAVLRQLLRLLPPRAGAKGGPAGLGLTPSAWEASSLRSSRHSGLSHF
  
Inhibitor
Name:
BDBM50156528
Synonyms:
CHEMBL3794185
Type:
Small organic molecule
Emp. Form.:
C21H23ClO5S
Mol. Mass.:
422.922
SMILES:
[H][C@]12C[C@@H](O)[C@H](COc3ccc(Cl)c(C)c3)[C@@]1([H])CC[C@@H](O2)c1csc(c1)C(O)=O |r|
Structure:
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