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Target
Transmembrane domain-containing protein TMIGD3
Ligand
BDBM50163880
Substrate
n/a
Meas. Tech.
ChEMBL_1573808 (CHEMBL3803229)
Ki
604±n/a nM
Citation
 Tosh, DK; Ciancetta, A; Warnick, E; O'Connor, R; Chen, Z; Gizewski, E; Crane, S; Gao, ZG; Auchampach, JA; Salvemini, D; Jacobson, KA Purine (N)-Methanocarba Nucleoside Derivatives Lacking an Exocyclic Amine as Selective A3 Adenosine Receptor Agonists. J Med Chem 59:3249-63 (2016) [PubMed]  Article 
Target
Name:
Transmembrane domain-containing protein TMIGD3
Synonyms:
TMIG3_HUMAN | TMIGD3 | Transmembrane domain-containing protein TMIGD3
Type:
PROTEIN
Mol. Mass.:
30335.79
Organism:
Homo sapiens (Human)
Description:
ChEMBL_114868
Residue:
266
Sequence:
MEGSPAGPIEQKEARWESSWEEQPDWTLGCLSPESQFRIPGLPGCILSFQLKVCFLPVMWLFILLSLALISDAMVMDEKVKRSFVLDTASAICNYNAHYKNHPKYWCRGYFRDYCNIIAFSPNSTNHVALRDTGNQLIVTMSCLTKEDTGWYWCGIQRDFARDDMDFTELIVTDDKGTLANDFWSGKDLSGNKTRSCKAPKVVRKADRSRTSILIICILITGLGIISVISHLTKRRRSQRNRRVGNTLKPFSRVLTPKEMAPTEQM
  
Inhibitor
Name:
BDBM50163880
Synonyms:
CHEMBL3800202
Type:
Small organic molecule
Emp. Form.:
C14H18N6O3
Mol. Mass.:
318.3311
SMILES:
[H][C@]12C[C@]1([C@@H](O)[C@@H](O)[C@@H]2n1cnc2cnc(NC)nc12)C(=O)NC |r|
Structure:
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