Reaction Details Report a problem with these data
Target
Calmodulin
Ligand
BDBM61401
Substrate
n/a
Meas. Tech.
ChEMBL_1572741 (CHEMBL3804250)
EC50
2100±n/a nM
Citation
 Bruno, C; Cavalluzzi, MM; Rusciano, MR; Lovece, A; Carrieri, A; Pracella, R; Giannuzzi, G; Polimeno, L; Viale, M; Illario, M; Franchini, C; Lentini, G The chemosensitizing agent lubeluzole binds calmodulin and inhibits Ca(2+)/calmodulin-dependent kinase II. Eur J Med Chem 116:36-45 (2016) [PubMed]  Article 
Target
Name:
Calmodulin
Synonyms:
CALM | CALM_BOVIN | CAM
Type:
PROTEIN
Mol. Mass.:
16813.73
Organism:
Bos taurus
Description:
ChEMBL_1458985
Residue:
149
Sequence:
MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK
  
Inhibitor
Name:
BDBM61401
Synonyms:
3,3-diphenyl-N-(1-phenylethyl)-1-propanamine;hydrochloride | 3,3-diphenyl-N-(1-phenylethyl)propan-1-amine;hydrochloride | 3,3-diphenylpropyl(1-phenylethyl)amine;hydrochloride | CHEMBL254832 | FENDILINE HYDROCHLORIDE | MLS000069570 | SMR000058827 | cid_5702162
Type:
Small organic molecule
Emp. Form.:
C23H25N
Mol. Mass.:
315.4513
SMILES:
CC(NCCC(c1ccccc1)c1ccccc1)c1ccccc1
Structure:
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