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Target
Beta-1 adrenergic receptor
Ligand
BDBM50166976
Substrate
n/a
Meas. Tech.
ChEMBL_1573518 (CHEMBL3801473)
Ki
150±n/a nM
Citation
 Weichert, D; Stanek, M; Hübner, H; Gmeiner, P Structure-guided development of dualß2 adrenergic/dopamine D2 receptor agonists. Bioorg Med Chem 24:2641-53 (2016) [PubMed]  Article 
Target
Name:
Beta-1 adrenergic receptor
Synonyms:
ADRB1_MOUSE | Adrb1 | Adrb1r | Beta-1 adrenergic recepto | Beta-1 adrenergic receptor | Beta-1 adrenoceptor | Beta-1 adrenoreceptor
Type:
PROTEIN
Mol. Mass.:
50507.75
Organism:
Mus musculus
Description:
ChEMBL_105090
Residue:
466
Sequence:
MGAGALALGASEPCNLSSAAPLPDGAATAARLLVLASPPASLLPPASEGSAPLSQQWTAGMGLLLALIVLLIVVGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVVWGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARALVCTVWAISALVSFLPILMHWWRAESDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIMAFVYLRVFREAQKQVKKIDSCERRFLGGPARPPSPEPSPSPGPPRPADSLANGRSSKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRDLVPDRLFVFFNWLGYANSAFNPIIYCRSPDFRKAFQRLLCCARRAACRRRAAHGDRPRASGCLARAGPPPSPGAPSDDDDDDAGTTPPARLLEPWTGCNGGTTTVDSDSSLDEPGRQGFSSESKV
  
Inhibitor
Name:
BDBM50166976
Synonyms:
CHEMBL3799455
Type:
Small organic molecule
Emp. Form.:
C29H32N2O4
Mol. Mass.:
472.5754
SMILES:
COc1cc(CCNCCc2ccc(O)c3[nH]c(=O)ccc23)ccc1OCCCc1ccccc1
Structure:
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