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Target
Sphingosine kinase 1
Ligand
BDBM50041978
Substrate
n/a
Meas. Tech.
ChEMBL_1582610 (CHEMBL3816951)
Ki
3.6±n/a nM
Citation
Congdon, MD; Kharel, Y; Brown, AM; Lewis, SN; Bevan, DR; Lynch, KR; Santos, WL Structure-Activity Relationship Studies and Molecular Modeling of Naphthalene-Based Sphingosine Kinase 2 Inhibitors. ACS Med Chem Lett 7:229-34 (2016) [PubMed] Article
More Info.:
Target
Name:
Sphingosine kinase 1
Synonyms:
SK 1 | SPHK1_MOUSE | SPK 1 | Sk1 | Sphk1
Type:
PROTEIN
Mol. Mass.:
42447.37
Organism:
Mouse
Description:
ChEMBL_107622
Residue:
382
Sequence:
MEPVECPRGLLPRPCRVLVLLNPQGGKGKALQLFQSRVQPFLEEAEITFKLILTERKNHARELVCAEELGHWDALAVMSGDGLMHEVVNGLMERPDWETAIQKPLCSLPGGSGNALAASVNHYAGYEQVTNEDLLINCTLLLCRRRLSPMNLLSLHTASGLRLYSVLSLSWGFVADVDLESEKYRRLGEIRFTVGTFFRLASLRIYQGQLAYLPVGTVASKRPASTLVQKGPVDTHLVPLEEPVPSHWTVVPEQDFVLVLVLLHTHLSSELFAAPMGRCEAGVMHLFYVRAGVSRAALLRLFLAMQKGKHMELDCPYLVHVPVVAFRLEPRSQRGVFSVDGELMVCEAVQGQVHPNYLWMVCGSRDAPSGRDSRRGPPPEEP