Reaction Details Report a problem with these data
Target
Peptide deformylase
Ligand
BDBM50179406
Substrate
n/a
Meas. Tech.
ChEMBL_1583803 (CHEMBL3815890)
IC50
3900±n/a nM
Citation
 Khan, FA; Patil, RH; Shinde, DB; Sangshetti, JN Bacterial Peptide deformylase inhibition of cyano substituted biaryl analogs: Synthesis, in vitro biological evaluation, molecular docking study and in silico ADME prediction. Bioorg Med Chem 24:3456-63 (2016) [PubMed]  Article 
Target
Name:
Peptide deformylase
Synonyms:
3.5.1.88 | BON69_24600 | BON94_18585 | D9G11_24945 | D9G11_25760 | D9J60_20755 | FORC82_p394 | PDF | Polypeptide deformylase | SAMEA3472033_04733 | def | def_2
Type:
n/a
Mol. Mass.:
16901.39
Organism:
Escherichia coli
Description:
n/a
Residue:
150
Sequence:
MSVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEKGIGLAATQVDIHQRIIVIDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALVPRAEKVKIRALDRDGKPFELEADGLLAICIGLRLGNGKYCTLRLFFNQV
  
Inhibitor
Name:
BDBM50179406
Synonyms:
CHEMBL3814850
Type:
Small organic molecule
Emp. Form.:
C24H21ClN6
Mol. Mass.:
428.917
SMILES:
CCCc1nc2ccc(Cl)cc2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Structure:
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