Target
Free fatty acid receptor 1
Ligand
BDBM50180892
Substrate
n/a
Meas. Tech.
ChEMBL_1585167 (CHEMBL3820975)
Kd
4.0±n/a nM
Citation
 Christiansen, EHudson, BDHansen, AHMilligan, GUlven, T Development and Characterization of a Potent Free Fatty Acid Receptor 1 (FFA1) Fluorescent Tracer. J Med Chem 59:4849-58 (2016) [PubMed]  Article 
Target
Name:
Free fatty acid receptor 1
Synonyms:
FFAR1 | FFAR1_HUMAN | G-protein Coupled Receptor 40 | GPR40
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
31473.32
Organism:
Homo sapiens (Human)
Description:
O14842
Residue:
300
Sequence:
MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAGPARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
  
Inhibitor
Name:
BDBM50180892
Synonyms:
CHEMBL3817889
Type:
Small organic molecule
Emp. Form.:
C33H31FN4O8
Mol. Mass.:
630.6196
SMILES:
Cc1cc(OCCOCCNc2ccc([N+]([O-])=O)c3nonc23)ccc1-c1cccc(COc2ccc(CCC(O)=O)c(F)c2)c1
Structure:
Search PDB for entries with ligand similarity: