Reaction Details Report a problem with these data
Target
Neuraminidase
Ligand
BDBM50181444
Substrate
n/a
Meas. Tech.
ChEMBL_1584614 (CHEMBL3820942)
IC50
0.300000±n/a nM
Citation
 Wang, PC; Fang, JM; Tsai, KC; Wang, SY; Huang, WI; Tseng, YC; Cheng, YS; Cheng, TJ; Wong, CH Peramivir Phosphonate Derivatives as Influenza Neuraminidase Inhibitors. J Med Chem 59:5297-310 (2016) [PubMed]  Article 
Target
Name:
Neuraminidase
Synonyms:
NA | NRAM_I33A0
Type:
PROTEIN
Mol. Mass.:
49687.56
Organism:
Influenza A virus
Description:
ChEMBL_1347422
Residue:
453
Sequence:
MNPNQKIITIGSICMVVGIISLILQIGNIISIWISHSIQTGNQNHTGICNQGIITYNVVAGQDSTSVILTGNSSLCPIRGWAIHSKDNGIRIGSKGDVFVIREPFISCSHLECRTFFLTQGALLNDKHSNGTVKDRSPYRALMSCPVGEAPSPYNSRFESVAWSASACHDGMGWLTIGISGPDNGAVAVLKYNGIITETIKSWRKKILRTQESECTCVNGSCFTIMTDGPSNGLASYKIFKIEKGKVTKSIELNAPNSHYEECSCYPDTGKVMCVCRDNWHGSNRPWVSFDQNLDYQIGYICSGVFGDNPRPKDGPGSCGPVSADGANGVKGFSYRYGNGVWIGRTKSDSSRHGFEMIWDPNGWTETDSRFSVRQDVVAMTDRSGYSGSFVQHPELTGLDCMRPCFWVELIRGRPEEETIWTSGSIISFCGVNSDTVDWSWPDGAELPFTIDK
  
Inhibitor
Name:
BDBM50181444
Synonyms:
CHEMBL3818436
Type:
Small organic molecule
Emp. Form.:
C14H27N4O4P
Mol. Mass.:
346.3623
SMILES:
[H][C@]1(C=C(C[C@H]1NC(N)=N)P(O)(O)=O)[C@@H](NC(C)=O)C(CC)CC |r,c:2|
Structure:
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