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Target
Neuraminidase
Ligand
BDBM50181447
Substrate
n/a
Meas. Tech.
ChEMBL_1584606 (CHEMBL3820775)
IC50
0.500000±n/a nM
Citation
 Wang, PC; Fang, JM; Tsai, KC; Wang, SY; Huang, WI; Tseng, YC; Cheng, YS; Cheng, TJ; Wong, CH Peramivir Phosphonate Derivatives as Influenza Neuraminidase Inhibitors. J Med Chem 59:5297-310 (2016) [PubMed]  Article 
Target
Name:
Neuraminidase
Synonyms:
NA | NRAM_I33A0
Type:
PROTEIN
Mol. Mass.:
49687.56
Organism:
Influenza A virus
Description:
ChEMBL_1347422
Residue:
453
Sequence:
MNPNQKIITIGSICMVVGIISLILQIGNIISIWISHSIQTGNQNHTGICNQGIITYNVVAGQDSTSVILTGNSSLCPIRGWAIHSKDNGIRIGSKGDVFVIREPFISCSHLECRTFFLTQGALLNDKHSNGTVKDRSPYRALMSCPVGEAPSPYNSRFESVAWSASACHDGMGWLTIGISGPDNGAVAVLKYNGIITETIKSWRKKILRTQESECTCVNGSCFTIMTDGPSNGLASYKIFKIEKGKVTKSIELNAPNSHYEECSCYPDTGKVMCVCRDNWHGSNRPWVSFDQNLDYQIGYICSGVFGDNPRPKDGPGSCGPVSADGANGVKGFSYRYGNGVWIGRTKSDSSRHGFEMIWDPNGWTETDSRFSVRQDVVAMTDRSGYSGSFVQHPELTGLDCMRPCFWVELIRGRPEEETIWTSGSIISFCGVNSDTVDWSWPDGAELPFTIDK
  
Inhibitor
Name:
BDBM50181447
Synonyms:
CHEMBL3819487
Type:
Small organic molecule
Emp. Form.:
C20H41N4O5P
Mol. Mass.:
448.5371
SMILES:
[H][C@@]1([C@@H](NC(C)=O)C(CC)CC)[C@H](O)[C@H](C[C@H]1NC(N)=N)P(O)(=O)OCCCCCC |r|
Structure:
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