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Target
Proliferating cell nuclear antigen
Ligand
BDBM50431467
Substrate
n/a
Meas. Tech.
ChEMBL_1612849 (CHEMBL3854649)
IC50
20000±n/a nM
Citation
 Korzhnev, DM; Hadden, MK Targeting the Translesion Synthesis Pathway for the Development of Anti-Cancer Chemotherapeutics. J Med Chem 59:9321-9336 (2016) [PubMed]  Article 
Target
Name:
Proliferating cell nuclear antigen
Synonyms:
Cyclin | PCNA | PCNA_HUMAN
Type:
PROTEIN
Mol. Mass.:
28752.86
Organism:
Homo sapiens (Human)
Description:
ChEMBL_952429
Residue:
261
Sequence:
MFEARLVQGSILKKVLEALKDLINEACWDISSSGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIKLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSSTVTLSMSADVPLVVEYKIADMGHLKYYLAPKIEDEEGS
  
Inhibitor
Name:
BDBM50431467
Synonyms:
CHEMBL2348305
Type:
Small organic molecule
Emp. Form.:
C15H15I2NO3
Mol. Mass.:
511.0934
SMILES:
N[C@H](CO)Cc1cc(I)c(Oc2ccc(O)cc2)c(I)c1 |r|
Structure:
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